About Us
Focus on Developing
A New Generation of
Drug Delivery Mechanism
Company
Overview
ImmVira is a biotechnology company focused on development of new generation novel anti-cancer drug vectors driven by clinical benefits in oncology and non-oncology fields. Leveraging naturally evolved delivery mechanisms and proprietary precise gene engineering technology, our products include replicating and non-replicating herpes simplex virus vector and drug delivery exosome. The company has developed science, technology and know-how to support ongoing research, development and commercialization of best-in-class mono and combo therapies on the OVPENS (Open Vector+ Potent, Enabling, Novel & Safe) platform. Our clinical stage and development stage pipelines target a wide range of solid tumors and hematologic malignancies as an initial validation of vector capability in oncology, to be used as single agent or combination treatment solutions for cancer patients at different stages, unresponsive to immunotherapy or with rare tumors, by various administration methods including intratumoral, as well as first-in-class intravenous and intraperitoneal/pleural/vesical injections. The first three oncolytic virus products are undergoing six Phase I or Phase II clinical trials in both United States and China.
Company History
2015-2016

MayEstablished in Shenzhen City

JunFirst PCT submission

Round A
2017-2018

JulConstruction of MVR- T3011

AugCompletion of CMC study with GMP Compliance

2019

JulMVR-T3011 IT IND Approval in China

SeptMVR-T3011 IT OGTR License Approval in Australia

Round A+
2020

AprMVR-T3011 IT Phase I FPI in China

MayMVR-T3011 IND Clearance in US

JunMVR-T3011 IT Phase I FPI in US/Australia

AugMVR-T3011 IT Greater China rights out-licensed to Shanghai Pharma

Round B Round B+ Round C
2021

MayMVR-T3011 IT Phase II FPI in China

JunMVR-T3011 IT Phase II FPI in US

JulPilot-scale production line launched in Shenzhen

AugMVR-T3011 IV IND Approval in China

AugMVR-C5252 IND Clearance in US

AugMVR-T3011 IV FPI in US

2022

MarMVR-T3011 IV Phase I FPI in China

AprJoint development with Roche on combo therapy of MVR-T3011 IT and MEKi in US

JulCo-development with CRBio on MVR-C5252 in Greater China Area

AugMVR-C5252 ODD (Malignant Glioma) obtained in US

2023

MarStrategic cooperation with Cytiva to jointly develop exosome scale-up process

NovMVR-T3011 IV LPI in US

NovMVR-T3011 IT Combo w/PD-1 IND Approval in China

Partners
Howard L. Kaufman, M.D.

CEO at Ankyra Therapeutics,
Former CMO at Replimune

Global leading authority on local tumor immunotherapy and oncolytic viruses

Lead the successful phase III trial of T-VEC

Ghassan Abou-Alfa, M.D.

Medical Oncologist, Memorial Sloan Kettering Cancer Center 

Jaxin (Jason) Niu, M.D., Ph.D.

Medical Oncologist, Banner MD Anderson Cancer Center at Banner Gateway Medical Center

Mustafa Khasraw, M.D.

Medical Oncologist, Neuro-oncologist, and 

Deputy Director of the Center for Cancer 

Immunotherapy, Duke Cancer Institute

Tong Guo, Ph.D.

IQVIA Greater China VP of BD

Former Executive Vice President at LinkDoc

IEPMA ICH M14 Expert Working Group Member

Ruyi He, Ph.D.

Former Chief Scientist, CDE